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Krekelberg Neuroscience Laboratory

  

Publications: liuetal

Name

liuetal 

Title

Immediate neurophysiological effects of transcranial electrical stimulation 

Abstract

Noninvasive brain stimulation techniques are used in experimental and clinical fields for their potential effects on brain network dynamics and behavior. Transcranial electrical stimulation (TES), including transcranial direct current stimulation (tDCS) and transcranial alternating current stimulation (tACS), has gained popularity because of its convenience and potential as a chronic therapy. However, a mechanistic understanding of TES has lagged behind its widespread adoption. Here, we review data and modelling on the immediate neurophysiological effects of TES in vitro as well as in vivo in both humans and other animals. While it remains unclear how typical TES protocols affect neural activity, we propose that validated models of current flow should inform study design and artifacts should be carefully excluded during signal recording and analysis. Potential indirect effects of TES (e.g., peripheral stimulation) should be investigated in more detail and further explored in experimental designs. We also consider how novel technologies may stimulate the next generation of TES experiments and devices, thus enhancing validity, specificity, and reproducibility.

Authors

Anli Liu, Mihály Vöröslakos, Greg Kronberg, Simon Henin, Matthew R. Krause, Yu Huang, Alexander Opitz, Ashesh Mehta, Christopher C. Pack, Bart Krekelberg, Antal Berényi, Lucas C. Parra, Lucia Melloni, Orrin Devinsky & György Buzsáki  

Bibliographic Information

Nature Communicationsvolume 9, Article number: 5092 (2018)  

Publication Date

11/30/2018 

PubType

Journal 

Year

2,018 

Reference

Anli Liu, Mihály Vöröslakos, Greg Kronberg, Simon Henin, Matthew R. Krause, Yu Huang, Alexander Opitz, Ashesh Mehta, Christopher C. Pack, Bart Krekelberg, Antal Berényi, Lucas C. Parra, Lucia Melloni, Orrin Devinsky & György Buzsáki .Immediate neurophysiological effects of transcranial electrical stimulation.Nature Communicationsvolume 9, Article number: 5092 (2018)  (2018) 

Publication

Immediate neurophysiological effects of transcranial electrical stimulation : Nature Communicationsvolume 9, Article number: 5092 (2018)  (2018) 
Content Type: Abstract
Created at 12/5/2018 8:13  by Bart Krekelberg 
Last modified at 12/5/2018 8:15  by Bart Krekelberg